T121N (p.Thr121Asn) variant of WWTR1 (Q9GZV5)
T121N (p.Thr121Asn) in WWTR1 (Q9GZV5) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.36 / 1. The record also includes population frequency data and structural context.
T121N (p.Thr121Asn) variant details
- p.Thr121Asn
- ExAC rs766632650
- TOPMed rs766632650
- gnomAD rs766632650
- Missense
- Variant Prioritization Score for Impact Estimate 0.357
- REVEL 0.09
- CADD 24.60
- PolyPhen-2 0.14
- SIFT 0.02
- Most common in the South Asian population (allele frequency 4.9e-05)
- Structural context available