T121I (p.Thr121Ile) variant of WWTR1 (Q9GZV5)
T121I (p.Thr121Ile) in WWTR1 (Q9GZV5) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.36 / 1. The record also includes population frequency data and structural context.
T121I (p.Thr121Ile) variant details
- p.Thr121Ile
- ExAC rs766632650
- TOPMed rs766632650
- gnomAD rs766632650
- Missense
- Variant Prioritization Score for Impact Estimate 0.358
- REVEL 0.09
- CADD 23.60
- PolyPhen-2 0.14
- SIFT 0.17
- Most common in the African/African-American population (allele frequency 4.8e-05)
- Structural context available