S58L (p.Ser58Leu) variant of WWTR1 (Q9GZV5)
S58L (p.Ser58Leu) in WWTR1 (Q9GZV5) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.44 / 1. The record also includes population frequency data and structural context.
S58L (p.Ser58Leu) variant details
- p.Ser58Leu
- Ensembl rs1576627460
- Missense
- Variant Prioritization Score for Impact Estimate 0.437
- REVEL 0.17
- CADD 31.00
- PolyPhen-2 0.62
- SIFT 0.05
- Most common in the Non-Finnish European population (allele frequency 1.8e-06)
- Structural context available