S105I (p.Ser105Ile) variant of WWTR1 (Q9GZV5)
S105I (p.Ser105Ile) in WWTR1 (Q9GZV5) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.26 / 1. The record also includes population frequency data and structural context.
S105I (p.Ser105Ile) variant details
- p.Ser105Ile
- TOPMed rs1318641028
- gnomAD rs1318641028
- Missense
- Variant Prioritization Score for Impact Estimate 0.258
- REVEL 0.11
- CADD 23.10
- PolyPhen-2 0.25
- SIFT 0.02
- Most common in the Non-Finnish European population (allele frequency 2.7e-06)
- Structural context available