S105G (p.Ser105Gly) variant of WWTR1 (Q9GZV5)
S105G (p.Ser105Gly) in WWTR1 (Q9GZV5) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.22 / 1. The record also includes population frequency data and structural context.
S105G (p.Ser105Gly) variant details
- p.Ser105Gly
- 1000Genomes rs566092490
- ExAC rs566092490
- gnomAD rs566092490
- Missense
- Variant Prioritization Score for Impact Estimate 0.22
- REVEL 0.06
- CADD 21.90
- PolyPhen-2 0.00
- SIFT 0.22
- Most common in the 1KG:ITU population (allele frequency 0.0049)
- Structural context available