R63L (p.Arg63Leu) variant of WWTR1 (Q9GZV5)
R63L (p.Arg63Leu) in WWTR1 (Q9GZV5) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.48 / 1. The record also includes population frequency data and structural context.
R63L (p.Arg63Leu) variant details
- p.Arg63Leu
- gnomAD rs1427667024
- Missense
- Variant Prioritization Score for Impact Estimate 0.484
- REVEL 0.25
- CADD 29.90
- PolyPhen-2 0.97
- SIFT 0.00
- Most common in the Finnish in Finland (FIN) population (allele frequency 9.4e-05)
- Structural context available