R63C (p.Arg63Cys) variant of WWTR1 (Q9GZV5)
R63C (p.Arg63Cys) in WWTR1 (Q9GZV5) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.52 / 1. The record also includes population frequency data and structural context.
R63C (p.Arg63Cys) variant details
- p.Arg63Cys
- cosmic curated COSV62292
- Ensembl rs1025385597
- Missense
- Variant Prioritization Score for Impact Estimate 0.521
- REVEL 0.31
- CADD 31.00
- PolyPhen-2 0.98
- SIFT 0.00
- Most common in the South Asian population (allele frequency 1.2e-05)
- Structural context available