R140M (p.Arg140Met) variant of WWTR1 (Q9GZV5)
R140M (p.Arg140Met) in WWTR1 (Q9GZV5) is a missense change. Clinical records from UniProt describe it as variant assessed as somatic; moderate impact. The available variant effect predictions contribute to a CATVariant prioritization score of 0.62 / 1. The record also includes population frequency data and structural context.
R140M (p.Arg140Met) variant details
- p.Arg140Met
- NCI-TCGA TCGA novel
- Variant assessed as somatic; moderate impact.
- Missense
- Variant Prioritization Score for Impact Estimate 0.619
- REVEL 0.64
- CADD 25.80
- PolyPhen-2 0.61
- SIFT 0.02
- UniProt: Variant assessed as somatic; moderate impact.
- Population evidence available
- Structural context available