R140K (p.Arg140Lys) variant of WWTR1 (Q9GZV5)
R140K (p.Arg140Lys) in WWTR1 (Q9GZV5) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.38 / 1. The record also includes population frequency data and structural context.
R140K (p.Arg140Lys) variant details
- p.Arg140Lys
- ExAC rs747164910
- TOPMed rs747164910
- gnomAD rs747164910
- Missense
- Variant Prioritization Score for Impact Estimate 0.378
- REVEL 0.26
- CADD 22.40
- PolyPhen-2 0.00
- SIFT 0.16
- Most common in the Non-Finnish European population (allele frequency 5.9e-05)
- Structural context available