R114C (p.Arg114Cys) variant of WWTR1 (Q9GZV5)
R114C (p.Arg114Cys) in WWTR1 (Q9GZV5) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.42 / 1. The record also includes population frequency data and structural context.
R114C (p.Arg114Cys) variant details
- p.Arg114Cys
- cosmic curated COSV62292
- Missense
- Variant Prioritization Score for Impact Estimate 0.416
- REVEL 0.26
- CADD 26.90
- PolyPhen-2 0.00
- SIFT 0.02
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available