Q15H (p.Gln15His) variant of WWTR1 (Q9GZV5)
Q15H (p.Gln15His) in WWTR1 (Q9GZV5) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.21 / 1. The record also includes population frequency data, experimental measurements, and structural context.
Q15H (p.Gln15His) variant details
- p.Gln15His
- ExAC rs779611911
- gnomAD rs779611911
- Missense
- Variant Prioritization Score for Impact Estimate 0.214
- REVEL 0.06
- CADD 19.80
- PolyPhen-2 0.00
- SIFT 0.41
- Most common in the Latino/Admixed American population (allele frequency 2.2e-05)
- Structural context available
- WWTR1 WW domain domainome 1.0: score -0.351