P9S (p.Pro9Ser) variant of WWTR1 (Q9GZV5)
P9S (p.Pro9Ser) in WWTR1 (Q9GZV5) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.19 / 1. The record also includes population frequency data, experimental measurements, and structural context.
P9S (p.Pro9Ser) variant details
- p.Pro9Ser
- TOPMed rs921827996
- gnomAD rs921827996
- Missense
- Variant Prioritization Score for Impact Estimate 0.186
- REVEL 0.05
- CADD 19.90
- PolyPhen-2 0.03
- SIFT 0.25
- Most common in the East Asian population (allele frequency 0.00019)
- Structural context available
- WWTR1 WW domain domainome 1.0: score -0.0347