P74Q (p.Pro74Gln) variant of WWTR1 (Q9GZV5)
P74Q (p.Pro74Gln) in WWTR1 (Q9GZV5) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.34 / 1. The record also includes population frequency data and structural context.
P74Q (p.Pro74Gln) variant details
- p.Pro74Gln
- cosmic curated COSV62290
- 1000Genomes rs1055153
- ESP rs1055153
- ExAC rs1055153
- Missense
- Variant Prioritization Score for Impact Estimate 0.339
- REVEL 0.10
- CADD 25.70
- PolyPhen-2 0.98
- SIFT 0.07
- Most common in the 1KG:KHV population (allele frequency 0.23)
- Structural context available