P127S (p.Pro127Ser) variant of WWTR1 (Q9GZV5)
P127S (p.Pro127Ser) in WWTR1 (Q9GZV5) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.86 / 1. The record also includes population frequency data and structural context.
P127S (p.Pro127Ser) variant details
- p.Pro127Ser
- ExAC rs773592492
- gnomAD rs773592492
- Missense
- Variant Prioritization Score for Impact Estimate 0.863
- REVEL 0.90
- CADD 32.00
- PolyPhen-2 1.00
- SIFT 0.00
- Most common in the East Asian population (allele frequency 7.7e-05)
- Structural context available