L143F (p.Leu143Phe) variant of WWTR1 (Q9GZV5)
L143F (p.Leu143Phe) in WWTR1 (Q9GZV5) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.65 / 1. The record also includes population frequency data and structural context.
L143F (p.Leu143Phe) variant details
- p.Leu143Phe
- cosmic curated COSV62291
- Missense
- Variant Prioritization Score for Impact Estimate 0.655
- REVEL 0.68
- CADD 29.60
- PolyPhen-2 0.98
- SIFT 0.00
- Population evidence available
- Structural context available