I146T (p.Ile146Thr) variant of WWTR1 (Q9GZV5)
I146T (p.Ile146Thr) in WWTR1 (Q9GZV5) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.39 / 1. The record also includes population frequency data and structural context.
I146T (p.Ile146Thr) variant details
- p.Ile146Thr
- ExAC rs777145948
- TOPMed rs777145948
- gnomAD rs777145948
- Missense
- Variant Prioritization Score for Impact Estimate 0.394
- REVEL 0.36
- CADD 23.30
- PolyPhen-2 0.05
- SIFT 0.01
- Most common in the African/African-American population (allele frequency 3.2e-05)
- Structural context available