H61L (p.His61Leu) variant of WWTR1 (Q9GZV5)
H61L (p.His61Leu) in WWTR1 (Q9GZV5) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.52 / 1. The record also includes population frequency data and structural context.
H61L (p.His61Leu) variant details
- p.His61Leu
- gnomAD rs1402893555
- Missense
- Variant Prioritization Score for Impact Estimate 0.518
- REVEL 0.42
- CADD 28.90
- PolyPhen-2 0.97
- SIFT 0.00
- Most common in the REMAINING population (allele frequency 1.7e-05)
- Structural context available