G59S (p.Gly59Ser) variant of WWTR1 (Q9GZV5)
G59S (p.Gly59Ser) in WWTR1 (Q9GZV5) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.40 / 1. The record also includes population frequency data and structural context.
G59S (p.Gly59Ser) variant details
- p.Gly59Ser
- TOPMed rs1477506447
- gnomAD rs1477506447
- Missense
- Variant Prioritization Score for Impact Estimate 0.396
- REVEL 0.13
- CADD 24.70
- PolyPhen-2 0.81
- SIFT 0.08
- Most common in the African/African-American population (allele frequency 2.4e-05)
- Structural context available