E55K (p.Glu55Lys) variant of WWTR1 (Q9GZV5)
E55K (p.Glu55Lys) in WWTR1 (Q9GZV5) is a missense change. Clinical records from UniProt describe it as variant assessed as somatic; moderate impact. The available variant effect predictions contribute to a CATVariant prioritization score of 0.38 / 1. The record also includes population frequency data and structural context.
E55K (p.Glu55Lys) variant details
- p.Glu55Lys
- NCI-TCGA TCGA novel
- Variant assessed as somatic; moderate impact.
- Missense
- Variant Prioritization Score for Impact Estimate 0.379
- REVEL 0.10
- CADD 25.40
- PolyPhen-2 0.68
- SIFT 0.08
- UniProt: Variant assessed as somatic; moderate impact.
- Population evidence available
- Structural context available