A92S (p.Ala92Ser) variant of WWTR1 (Q9GZV5)
A92S (p.Ala92Ser) in WWTR1 (Q9GZV5) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.47 / 1. The record also includes population frequency data and structural context.
A92S (p.Ala92Ser) variant details
- p.Ala92Ser
- TOPMed rs1713277666
- Missense
- Variant Prioritization Score for Impact Estimate 0.468
- REVEL 0.24
- CADD 27.90
- PolyPhen-2 0.99
- SIFT 0.04
- Most common in the Latino/Admixed American population (allele frequency 6.5e-05)
- Structural context available