T12M (p.Thr12Met) variant of WWOX (Q9NZC7)
T12M (p.Thr12Met) in WWOX (Q9NZC7) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.69 / 1. The record also includes population frequency data, published literature, and structural context.
T12M (p.Thr12Met) variant details
- p.Thr12Met
- gnomAD 16-78099813-C-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.694
- CADD 28.60
- PolyPhen-2 0.94
- SIFT 0.00
- Most common in the Non-Finnish European population (allele frequency 9.1e-07)
- Structural context available
- Literature evidence available