L18P (p.Leu18Pro) variant of WWOX (Q9NZC7)
L18P (p.Leu18Pro) in WWOX (Q9NZC7) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.68 / 1. The record also includes population frequency data, published literature, and structural context.
L18P (p.Leu18Pro) variant details
- p.Leu18Pro
- gnomAD 16-78099831-T-C
- Missense
- Variant Prioritization Score for Impact Estimate 0.681
- CADD 32.00
- PolyPhen-2 1.00
- SIFT 0.00
- Most common in the Latino/Admixed American population (allele frequency 2.5e-05)
- Structural context available
- Literature evidence available