D10Y (p.Asp10Tyr) variant of WWOX (Q9NZC7)
D10Y (p.Asp10Tyr) in WWOX (Q9NZC7) is a missense change. Clinical records from ClinVar, EBI, and UniProt describe it as uncertain significance in the context of not provided. The available variant effect predictions contribute to a CATVariant prioritization score of 0.73 / 1. The record also includes population frequency data and structural context.
D10Y (p.Asp10Tyr) variant details
- p.Asp10Tyr
- rs781180473
- ClinGen CA396841775
- ClinVar RCV001755320
- ExAC rs781180473
- Uncertain significance
- not provided
- Missense
- Variant Prioritization Score for Impact Estimate 0.726
- CADD 24.00
- PolyPhen-2 0.25
- SIFT 0.05
- ClinVar: Uncertain significance (not provided)
- EBI: Variant of uncertain significance
- UniProt: Uncertain significance
- Population evidence available
- Structural context available