T443S (p.Thr443Ser) variant of WT1 (Wilms tumor protein)
T443S (p.Thr443Ser) in WT1 (Wilms tumor protein) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.37 / 1. The record also includes population frequency data, published literature, and structural context.
T443S (p.Thr443Ser) variant details
- p.Thr443Ser
- rs751932589
- gnomAD 11-32392041-T-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.373
- REVEL 0.24
- MetaLR 0.08
- MetaSVM -1.15
- CADD 24.50
- PolyPhen-2 0.62
- SIFT 0.16
- Population evidence available
- Structural context available
- Literature evidence available