T443N (p.Thr443Asn) variant of WT1 (Wilms tumor protein)
T443N (p.Thr443Asn) in WT1 (Wilms tumor protein) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.42 / 1. The record also includes population frequency data, published literature, and structural context.
T443N (p.Thr443Asn) variant details
- p.Thr443Asn
- rs766697865
- gnomAD 11-32392040-G-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.418
- REVEL 0.22
- MetaLR 0.10
- MetaSVM -1.17
- CADD 26.40
- PolyPhen-2 0.91
- SIFT 0.05
- Population evidence available
- Structural context available
- Literature evidence available