S428L (p.Ser428Leu) variant of WT1 (Wilms tumor protein)
S428L (p.Ser428Leu) in WT1 (Wilms tumor protein) is a protein-truncating change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.83 / 1. The record also includes population frequency data, published literature, and structural context.
S428L (p.Ser428Leu) variant details
- p.Ser428Leu
- gnomAD 11-32392022-G-GTA
- Frameshift
- Variant Prioritization Score for Impact Estimate 0.832
- CADD 34.00
- Population evidence available
- Structural context available
- Literature evidence available