S428F (p.Ser428Phe) variant of WT1 (Wilms tumor protein)
S428F (p.Ser428Phe) in WT1 (Wilms tumor protein) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.52 / 1. The record also includes population frequency data, published literature, and structural context.
S428F (p.Ser428Phe) variant details
- p.Ser428Phe
- rs1421664466
- gnomAD 11-32392022-G-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.524
- REVEL 0.40
- MetaLR 0.14
- MetaSVM -0.87
- CADD 31.00
- PolyPhen-2 1.00
- SIFT 0.04
- Population evidence available
- Structural context available
- Literature evidence available