R440W (p.Arg440Trp) variant of WT1 (Wilms tumor protein)
R440W (p.Arg440Trp) in WT1 (Wilms tumor protein) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.58 / 1. The record also includes population frequency data, published literature, and structural context.
R440W (p.Arg440Trp) variant details
- p.Arg440Trp
- rs1315549918
- gnomAD 11-32389159-G-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.576
- REVEL 0.48
- MetaLR 0.29
- MetaSVM -0.69
- CADD 32.00
- PolyPhen-2 1.00
- SIFT 0.00
- Population evidence available
- Structural context available
- Literature evidence available