R440P (p.Arg440Pro) variant of WT1 (Wilms tumor protein)
R440P (p.Arg440Pro) in WT1 (Wilms tumor protein) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.58 / 1. The record also includes population frequency data, published literature, and structural context.
R440P (p.Arg440Pro) variant details
- p.Arg440Pro
- rs139893274
- gnomAD 11-32389158-C-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.58
- REVEL 0.53
- MetaLR 0.12
- MetaSVM -0.64
- CADD 29.00
- PolyPhen-2 0.99
- SIFT 0.00
- Population evidence available
- Structural context available
- Literature evidence available