R433S (p.Arg433Ser) variant of WT1 (Wilms tumor protein)
R433S (p.Arg433Ser) in WT1 (Wilms tumor protein) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.37 / 1. The record also includes population frequency data, published literature, and structural context.
R433S (p.Arg433Ser) variant details
- p.Arg433Ser
- rs1851852809
- gnomAD 11-32392712-C-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.366
- REVEL 0.27
- MetaLR 0.02
- MetaSVM -1.01
- CADD 22.60
- PolyPhen-2 0.08
- SIFT 0.15
- Population evidence available
- Structural context available
- Literature evidence available