Q446R (p.Gln446Arg) variant of WT1 (Wilms tumor protein)
Q446R (p.Gln446Arg) in WT1 (Wilms tumor protein) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.39 / 1. The record also includes population frequency data, published literature, and structural context.
Q446R (p.Gln446Arg) variant details
- p.Gln446Arg
- gnomAD 11-32392049-T-C
- Missense
- Variant Prioritization Score for Impact Estimate 0.386
- REVEL 0.27
- MetaLR 0.09
- MetaSVM -0.97
- CADD 25.10
- PolyPhen-2 0.56
- SIFT 0.01
- Population evidence available
- Structural context available
- Literature evidence available