L449R (p.Leu449Arg) variant of WT1 (Wilms tumor protein)
L449R (p.Leu449Arg) in WT1 (Wilms tumor protein) is a protein-truncating change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.73 / 1. The record also includes population frequency data, published literature, and structural context.
L449R (p.Leu449Arg) variant details
- p.Leu449Arg
- rs1253058174
- gnomAD 11-32392006-CA-C
- Frameshift
- Variant Prioritization Score for Impact Estimate 0.732
- CADD 33.00
- Population evidence available
- Structural context available
- Literature evidence available