F425S (p.Phe425Ser) variant of WT1 (Wilms tumor protein)
F425S (p.Phe425Ser) in WT1 (Wilms tumor protein) is a protein-truncating change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.87 / 1. The record also includes population frequency data, published literature, and structural context.
F425S (p.Phe425Ser) variant details
- p.Phe425Ser
- gnomAD 11-32392020-GGGAG
- Frameshift
- Variant Prioritization Score for Impact Estimate 0.866
- CADD 33.00
- Population evidence available
- Structural context available
- Literature evidence available