F425L (p.Phe425Leu) variant of WT1 (Wilms tumor protein)
F425L (p.Phe425Leu) in WT1 (Wilms tumor protein) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.54 / 1. The record also includes population frequency data, published literature, and structural context.
F425L (p.Phe425Leu) variant details
- p.Phe425Leu
- rs1430665640
- gnomAD 11-32392024-G-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.544
- REVEL 0.64
- MetaLR 0.42
- MetaSVM -0.12
- CADD 26.90
- PolyPhen-2 0.99
- SIFT 0.02
- Population evidence available
- Structural context available
- Literature evidence available