D429Y (p.Asp429Tyr) variant of WT1 (Wilms tumor protein)
D429Y (p.Asp429Tyr) in WT1 (Wilms tumor protein) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.57 / 1. The record also includes population frequency data, published literature, and structural context.
D429Y (p.Asp429Tyr) variant details
- p.Asp429Tyr
- rs771494968
- gnomAD 11-32392735-C-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.566
- REVEL 0.49
- MetaLR 0.16
- MetaSVM -0.91
- CADD 29.50
- PolyPhen-2 0.99
- SIFT 0.00
- Population evidence available
- Structural context available
- Literature evidence available