Y57Y (p.Tyr57Tyr) variant of WRN (Q14191)
Y57Y (p.Tyr57Tyr) in WRN (Q14191) is a synonymous change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.36 / 1. The record also includes population frequency data, published literature, and structural context.
Y57Y (p.Tyr57Tyr) variant details
- p.Tyr57Tyr
- rs373806031
- gnomAD 8-31059227-C-T
- Synonymous
- Variant Prioritization Score for Impact Estimate 0.364
- CADD 5.18
- Most common in the African/African-American population (allele frequency 2.4e-05)
- Structural context available
- Literature evidence available