W18* (p.Trp18Ter) variant of WRN (Q14191)
W18* (p.Trp18Ter) in WRN (Q14191) is a protein-truncating change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.84 / 1. The record also includes population frequency data and structural context.
W18* (p.Trp18Ter) variant details
- p.Trp18Ter
- gnomAD rs1812360699
- Stop Gained
- Variant Prioritization Score for Impact Estimate 0.843
- CADD 36.00
- Most common in the African/African-American population (allele frequency 2.4e-05)
- Structural context available