T9S (p.Thr9Ser) variant of WRN (Q14191)
T9S (p.Thr9Ser) in WRN (Q14191) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.04 / 1. The record also includes population frequency data, published literature, and structural context.
T9S (p.Thr9Ser) variant details
- p.Thr9Ser
- gnomAD 8-31058472-A-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.0366
- REVEL 0.03
- CADD 0.12
- PolyPhen-2 0.01
- SIFT 0.09
- Most common in the Middle Eastern population (allele frequency 0.00017)
- Structural context available
- Literature evidence available