T50T (p.Thr50Thr) variant of WRN (Q14191)
T50T (p.Thr50Thr) in WRN (Q14191) is a synonymous change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.51 / 1. The record also includes population frequency data, published literature, and structural context.
T50T (p.Thr50Thr) variant details
- p.Thr50Thr
- rs1457303497
- gnomAD 8-31059206-T-G
- Synonymous
- Variant Prioritization Score for Impact Estimate 0.508
- CADD 8.35
- Most common in the Latino/Admixed American population (allele frequency 2.2e-05)
- Structural context available
- Literature evidence available