R31S (p.Arg31Ser) variant of WRN (Q14191)
R31S (p.Arg31Ser) in WRN (Q14191) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.13 / 1. The record also includes population frequency data and structural context.
R31S (p.Arg31Ser) variant details
- p.Arg31Ser
- TOPMed rs1296225830
- gnomAD rs1296225830
- Missense
- Variant Prioritization Score for Impact Estimate 0.135
- REVEL 0.03
- CADD 22.60
- PolyPhen-2 0.01
- SIFT 0.02
- Most common in the Non-Finnish European population (allele frequency 1.5e-05)
- Structural context available