F46F (p.Phe46Phe) variant of WRN (Q14191)
F46F (p.Phe46Phe) in WRN (Q14191) is a synonymous change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.36 / 1. The record also includes population frequency data, published literature, and structural context.
F46F (p.Phe46Phe) variant details
- p.Phe46Phe
- gnomAD 8-31059194-C-T
- Synonymous
- Variant Prioritization Score for Impact Estimate 0.359
- CADD 11.50
- Most common in the East Asian population (allele frequency 2.5e-05)
- Structural context available
- Literature evidence available