E3G (p.Glu3Gly) variant of WRN (Q14191)
E3G (p.Glu3Gly) in WRN (Q14191) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.12 / 1. The record also includes population frequency data and structural context.
E3G (p.Glu3Gly) variant details
- p.Glu3Gly
- TOPMed rs1441274369
- gnomAD rs1441274369
- Missense
- Variant Prioritization Score for Impact Estimate 0.119
- REVEL 0.03
- CADD 13.80
- PolyPhen-2 0.12
- SIFT 0.07
- Most common in the Latino/Admixed American population (allele frequency 6.5e-05)
- Structural context available