D61G (p.Asp61Gly) variant of WRN (Q14191)
D61G (p.Asp61Gly) in WRN (Q14191) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.57 / 1. The record also includes population frequency data and structural context.
D61G (p.Asp61Gly) variant details
- p.Asp61Gly
- ExAC rs752345825
- gnomAD rs752345825
- Missense
- Variant Prioritization Score for Impact Estimate 0.572
- REVEL 0.53
- CADD 26.00
- PolyPhen-2 1.00
- SIFT 0.00
- Most common in the Finnish in Finland (FIN) population (allele frequency 1.9e-05)
- Structural context available