D58E (p.Asp58Glu) variant of WRN (Q14191)
D58E (p.Asp58Glu) in WRN (Q14191) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.24 / 1. The record also includes population frequency data and structural context.
D58E (p.Asp58Glu) variant details
- p.Asp58Glu
- gnomAD rs1368177548
- Missense
- Variant Prioritization Score for Impact Estimate 0.239
- REVEL 0.09
- CADD 1.63
- PolyPhen-2 0.00
- SIFT 1.00
- Most common in the Non-Finnish European population (allele frequency 3.6e-06)
- Structural context available