D58D (p.Asp58Asp) variant of WRN (Q14191)
D58D (p.Asp58Asp) in WRN (Q14191) is a synonymous change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.46 / 1. The record also includes population frequency data, published literature, and structural context.
D58D (p.Asp58Asp) variant details
- p.Asp58Asp
- gnomAD 8-31059230-T-C
- Synonymous
- Variant Prioritization Score for Impact Estimate 0.462
- CADD 4.35
- Most common in the Middle Eastern population (allele frequency 0.00017)
- Structural context available
- Literature evidence available