C26R (p.Cys26Arg) variant of WRN (Q14191)
C26R (p.Cys26Arg) in WRN (Q14191) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.08 / 1. The record also includes population frequency data and structural context.
C26R (p.Cys26Arg) variant details
- p.Cys26Arg
- gnomAD rs1230077323
- Missense
- Variant Prioritization Score for Impact Estimate 0.0814
- REVEL 0.04
- CADD 9.89
- PolyPhen-2 0.00
- SIFT 0.59
- Most common in the East Asian population (allele frequency 2.5e-05)
- Structural context available