V105A (p.Val105Ala) variant of WDR45 (Q9Y484)
V105A (p.Val105Ala) in WDR45 (Q9Y484) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.47 / 1. The record also includes population frequency data and structural context.
V105A (p.Val105Ala) variant details
- p.Val105Ala
- Ensembl rs2065039866
- Missense
- Variant Prioritization Score for Impact Estimate 0.469
- REVEL 0.42
- CADD 23.50
- PolyPhen-2 0.15
- SIFT 0.02
- Most common in the Non-Finnish European population (allele frequency 1.2e-06)
- Structural context available