T100I (p.Thr100Ile) variant of WDR45 (Q9Y484)
T100I (p.Thr100Ile) in WDR45 (Q9Y484) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.44 / 1. The record also includes population frequency data and structural context.
T100I (p.Thr100Ile) variant details
- p.Thr100Ile
- gnomAD rs1557084316
- Missense
- Variant Prioritization Score for Impact Estimate 0.435
- REVEL 0.27
- CADD 22.50
- PolyPhen-2 0.04
- SIFT 0.16
- Most common in the REMAINING population (allele frequency 4.3e-05)
- Structural context available