L106F (p.Leu106Phe) variant of WDR45 (Q9Y484)
L106F (p.Leu106Phe) in WDR45 (Q9Y484) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.41 / 1. The record also includes population frequency data and structural context.
L106F (p.Leu106Phe) variant details
- p.Leu106Phe
- ExAC rs782725867
- gnomAD rs782725867
- Missense
- Variant Prioritization Score for Impact Estimate 0.409
- REVEL 0.44
- CADD 23.20
- PolyPhen-2 0.39
- SIFT 0.15
- Most common in the Latino/Admixed American population (allele frequency 2.8e-05)
- Structural context available