K89E (p.Lys89Glu) variant of WDR45 (Q9Y484)
K89E (p.Lys89Glu) in WDR45 (Q9Y484) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.25 / 1. The record also includes population frequency data and structural context.
K89E (p.Lys89Glu) variant details
- p.Lys89Glu
- TOPMed rs1460544405
- gnomAD rs1460544405
- Missense
- Variant Prioritization Score for Impact Estimate 0.251
- REVEL 0.05
- CADD 22.30
- PolyPhen-2 0.03
- SIFT 0.08
- Most common in the Non-Finnish European population (allele frequency 3.8e-05)
- Structural context available